Finally, my MetaFrame Presentation Client is up and running, after a couple trails. Just note my solution here. 1. ERROR: The supplied credentials were invalid. Please try again or contact your system administrator for help. The username or password is not correct. I found this when I try with another account. 2. Cannot connect to the Citrix XenApp server. There is no route to the specified subnet address I downloaded Update for Windows XP Service Pack 2 (KB884020) from http://www.microsoft.com/download/en/details.aspx?id=17235 ( Hot link : http://download.microsoft.com/ download/7/4/9/749eef31-7d91- 4558-88e3-7bfe92c212fc/ WindowsXP-KB884020-x86-enu.exe ) After I installed that and try to run again Secure Application Manager on the tray gives me something. There is an wfica32.exe application running, but it can send only 2843 Bytes and it failed with another error. The network connection to your application was interrupted. Try to access your application later, or contact your help ...